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序号 | API | Intermediate | CAS |
1 | 马昔替坦 Macitentan | 5-(4-溴苯基)-6-羟基嘧啶-4(1H)-酮 5-(4-Bromo phenyl) -6-hydroxy pyrimidn-4(1H) -one | 706811-25-8 |
5-(4-溴苯基)-4,6-二氯嘧啶 5-(4-Bromo phe ny) 4, 6-dichloro pyrimidine | 146533-41-7 | ||
N-[5-(4-溴苯基)-6-氯-4-嘧啶基]-N'-丙基氨基磺酰胺 (N-2)N-[5-(4-broMo phe ny-6-chloro-4-pyriMidinyl-N-propyl-Sulf aMide | 1393813-42-7 | ||
N-[5-(4-溴苯基)-6-(2-羟基乙氧基)-4-嘧啶基]-N'-丙基氨基磺酰胺(N-1) N-[5-(4-Bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-N'-propylsulfamide | 1393813-43-8 | ||
2 | 伐尼克兰 Varenicline | 2,3,4,5-四氢-1,5-甲桥-1H-3-苯并氮杂卓盐酸盐 2, 3, 4, 5-Tetrahydro-1,5-methano-1H-3-benzazepine hydrochloride | 230615-52-8 |
2,3,4,5-四氢-3-(三氟乙酰基)-1,5-甲桥-1H-3-苯并氮杂卓 2,3,4,5-Tetrahydro-3-(trifluoroacetyl) -1,5-methano-1H-3-benzazepine | 230615-51-7 | ||
2,3,4,5-四氢-7,8-二硝基-3-(三氟乙酰基)-1,5-甲桥-1H-3-苯并氮杂卓 2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl) -1,5-methano-1H-3-benzazepine | 230615-59-5 | ||
2,3,4,5-四氢-3-(三氟乙酰基)-1,5-甲桥-1H-3-苯并氮杂卓-7,8-二胺(N-2) 2,3,4,5-Tetrahydro-3-(trifluoroacetyl) -1, 5-methano-1H-3-benzazepine-7, 8-damine | 230615-69-7 | ||
7,8,9,10-四氢-8-(三氟乙酰基)-6,10-甲桥-6H-吡嗪并[2,3-h][3]苯并氮杂卓(N-1) 6,10-Methano-6H-pyrazino[2,3-h] [3] benzazepine,7,8,9,10-tetrahydro-8(trluoroacetyl) | 230615-70-0 | ||
伐尼克兰 Varenicline | 249296-44-4 | ||
3 | 西那卡塞 Cinacalcet | 间三氟甲基肉桂酸 3-(Trifluoromethyl) cinnamic acid | 779-89-5 |
3-(3-三氟甲基苯基)丙酸 3-(3-TrifluoromethyIphenyl) propionic acid | 585-50-2 | ||
3-(3-三氟甲基苯基)丙醇 3-(Trifluoromethyl) benzene propanol | 78573-45-2 | ||
4 | 沃诺拉赞 Vonoprazan | 5-(2-氟苯基)-1H-吡咯-3-甲腈 5-(2-Fluorophenyl) -1H-pyrrole-3-carbonitrile | 1240948-77-9 |
5-(2-氟苯基)-1H-吡咯-3-甲醛 5-(2-Fluorophenyl-1H-pyrrole-3-carboxaldehyde | 881674-56-2 | ||
5-(2-氟苯基)-1-[(吡啶-3-基)磺酰基]-1H-吡咯-3-甲醛(N-2) 5-(2-fluorophenyl-1-(pyridin-3-ylsulfonyl) -1H-pyrrole-3-carbaldehyde | 881677-11-8 | ||
5 | 伊曲茶碱 Itraphylline | 3,4-二甲氧基肉桂酸 3,4-Dimethoxy cinnamic acid | 14737-89-4 |
(2E) -3,4-二甲氧基苯丙酰氯 (2E) -3-(3,4-dimethoxyphenyl) prop-2-enoyl chloride | 141236-46-6 | ||
1.3-二乙基-5-亚硝基-6-氨基脲嘧啶. 1,3-Diethyl-5-Nitro-6-Amino Uracil | 89073-60-9 | ||
5,6-二氨基-1,3-二乙基尿嘧啶盐酸盐 5,6-Diamino-1,3-diethyl uracil Hydrochloride | 1785764-26-2 | ||
(E)-1.3-二乙基-6-氨基-5-(3,4-二甲氧基苯丙烯酰基)氨基尿嘧啶(N-2) (E) -N-6-aMino-1, 3-diet yl-2, 4-dioxo-1, 2.3, 4-tetrahydro pyr iMd in-5-yl-3-(3, 4-diMehoxypheny) acrylaMide | 187393-68-6 | ||
8-[(1E)-2-(3,4-二甲氧基苯基)乙烯基]-1.3-二乙基-3,9-二氢-1H-嘌呤-2,6-二酮(N-1) 8-[(1E) -2-(3,4-Dimethoxy phenyI) ethenyl] -1,3-diethyl-3,9-dihydro-1H-purine-2, 6-dione | 155270-98-7 | ||
6 | 托匹司他 Topiroxostat | 4-氰基吡啶-1-氧化物4-Cyano pyridinium-1-olate | 14906-59-3 |
4-[5-(1-氧化-4-吡啶)-1H-1,2,4-噻唑-3-基]吡啶(托匹司他中间体1). Pyridine, 4-[5-(4-pyridinyl) -1H-1, 2, 4-tri azo-3-yl] -, l-oxide | 36770-53-3 | ||
4-(1-((苄氧基)甲基)-5-(吡啶-4-基)-1H-1,2,4-三唑-3-基)吡啶甲腈(N-1) 4-(1-(benzylxy) methyl) -5-(pyridin-4-y-1H-1,2, 4-triazol-3-yl) picolinonitrile | 837371-70-7 | ||
7 | 非索罗定 Fesoterodine | 5-羟甲基托特罗定(N-2) 5-HydroxyMethyl Tolterodinel | 200801-70-3 |
(R)-5-羟甲基托特罗定(N-1) (R) -5-HydroxyMethyl Tolterodinel | 207679-81-0 | ||
8 | 培哚普利 Perindopril | (S)-吲哚啉-2-羧酸. (S) -(-) -Indoline-2-carboxylic acid | 79815-20-6 |
(2S,3aS,7aS)-八氢-1H-吲哚-2-羧酸(2S,3aS,7aS-Octahydro-1H-indole-2-carboxylic acid | 80875-98-5 | ||
N-[(S)-乙氧羰基-1-丁基]-(S)-丙氨酸 N-(S) -1-Carbethoxy-1-butyl] -(S) -alanine | 82834-12-6 | ||
9 | 安那度尔 alphaprodine | 1,3-二甲基-4-哌啶酮 1,3-Dimethyl piperidin-4-one | 4629-80-5 |
10 | 盐酸齐拉西酮 Ziprasidone | 6-氯吲哚-2-酮 6-Chloro-2-oxoindole | 56341-37-8 |
11 | 卡利拉嗪 Cariprazine | 反式-4-氨基环己烷乙酸 (trans-4-Aminocyclohexyl) acetic acid | 2952-00-3 |
12 | 维生素K1;K2 Vitamin K 1;K 2 | MK-7中间体 MK-7 intermediate | 97804-50-7 |
13 | 降冰片烯系列 NBE Series | 环戊二烯(单体) 1,3-Cyclopentadiene | 542-92-7 |
2-氰基-5-降冰片烯5-Norbornene-2-carbontrile | 95-11-4 | ||
2-氯双环[2.2.1]庚-5-烯-2-甲腈 2-chlorobicyclo[2.2.1] hept-5-ene-2-carbonitrile | 6945-87-5 | ||
5-降冰片烯-2羧酸5-Norbornene-2-carboxylic acid | 120-74-1 | ||
14 | 环己酮系列 | 4-环己酮甲酸乙酯 4-oxo-cyclohexane carboxylicaciethyleste | 17159-79-4 |
15 | 反式酸系列 | 反式对甲基环己甲酸 Trans-p-Methyl cyclohexane carboxylic acid | 13064-83-0 |
反式对异丙基环己基甲酸 Trans-4-lsopropylcyclohexane Carboxylic Acid | 7077-05-6 | ||
16 | 喹啉系列 | 1,2,3,4-四氢喹啉 1.2.3, 4-Tetrahydroquinoline | 635-46-1 |
1,2,3,4-四氢异喹啉 1, 2.3, 4-tetrahydro-isoquinolin | 91-21-4 | ||
5,6,7,8-四氢喹啉 5, 6.7.8-four hydrogenation of quinoline | 10500-57-9 |